Link Prediction in Protein-Protein Networks: Survey

نویسندگان

  • Manu Kurakar
  • Sminu Izudheen
چکیده

Protein networks have a great importance in biological activities. ProteinProtein interaction occurs when two or more proteins interact together to carry out some biological activities. For example signals from the exterior of a cell are mediated to the interior through these interactions. Identification of these interaction have a great significance in understanding complex diseases and also for designing drugs. With the availability of huge biological data, computational biology is at position such that, it can predict missing protein protein interactions. Here, this article summarizes technologies for missing link prediction.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Prediction of Protein Sub-Mitochondria Locations Using Protein Interaction Networks

Background: Prediction of the protein localization is among the most important issues in the bioinformatics that is used for the prediction of the proteins in the cells and organelles such as mitochondria. In this study, several machine learning algorithms are applied for the prediction of the intracellular protein locations. These algorithms use the features extracted from pro...

متن کامل

A Link Prediction Method Based on Learning Automata in Social Networks

Nowadays, online social networks are considered as one of the most important emerging phenomena of human societies. In these networks, prediction of link by relying on the knowledge existing of the interaction between network actors provides an estimation of the probability of creation of a new relationship in future. A wide range of applications can be found for link prediction such as electro...

متن کامل

Study of PKA binding sites in cAMP-signaling pathway using structural protein-protein interaction networks

Backgroud: Protein-protein interaction, plays a key role in signal transduction in signaling pathways. Different approaches are used for prediction of these interactions including experimental and computational approaches. In conventional node-edge protein-protein interaction networks, we can only see which proteins interact but ‘structural networks’ show us how these proteins inter...

متن کامل

Protein Secondary Structure Prediction: a Literature Review with Focus on Machine Learning Approaches

DNA sequence, containing all genetic traits is not a functional entity. Instead, it transfers to protein sequences by transcription and translation processes. This protein sequence takes on a 3D structure later, which is a functional unit and can manage biological interactions using the information encoded in DNA. Every life process one can figure is undertaken by proteins with specific functio...

متن کامل

Link Prediction using Network Embedding based on Global Similarity

Background: The link prediction issue is one of the most widely used problems in complex network analysis. Link prediction requires knowing the background of previous link connections and combining them with available information. The link prediction local approaches with node structure objectives are fast in case of speed but are not accurate enough. On the other hand, the global link predicti...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014